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Clinicaltrials.gov was searched for registered analyze protocols. The keywords “palmitoylethanolamide” and “discomfort” resulted in thirteen entries, of which 3 were completed. None of these fulfilled our eligibility conditions.The datasets created and/or analyzed through The existing review can be found through the corresponding writer on
In these problems, it has been shown that the increase of endogenous Palmitoylethanolamide—either by decreasing its degradation or exogenous administration—is able to maintain neuroinflammation in its physiological limitations. Within this overview the massive amount of experiments on the advantages derived from oral administration of micronize